Scientific clarity for the molecules that matter.

Aalo Bio partners with biotech and pharmaceutical teams on drug discovery, medicinal chemistry, and R&D strategy, from first hit to development candidate and the decisions in between.

Discuss your program See our services

What we do

Hands-on scientific expertise and senior strategic judgment, applied where your program needs it most.

Drug discovery R&D

Support across the discovery pipeline, helping you move from hit to development candidate with fewer wasted cycles.

  • Hit identification, hit-to-lead, and lead optimization
  • Screening strategy, including fragment-based and DEL approaches
  • Design-make-test-analyze cycle planning with CROs
  • Preclinical candidate selection and nomination
  • Planning for in vivo and IND-enabling studies

Medicinal chemistry

Expert design thinking to solve potency, selectivity, and developability problems, across small molecules and beyond.

  • SAR analysis and multiparameter optimization
  • Structure-based and computer-aided drug design, including AI tools
  • ADME, DMPK, and developability optimization
  • Small molecules, heterocycles, peptides, oligonucleotides, peptidomimetics, carbohydrates, and bioconjugates
  • Route design, scale-up, and CRO chemistry oversight

Strategy & advisory

Independent counsel for leadership teams, boards, and investors facing high-stakes R&D decisions.

  • R&D and medicinal chemistry strategy
  • Scientific due diligence and asset evaluation
  • API and excipient supply chain risk assessment
  • CMC data review and regulatory documentation support
  • Patent preparation support and scientific advisory roles

Who we help

We work with organizations at every stage, adapting to the size and pace of your team.

Early-stage biotech

Founding teams who need experienced drug discovery leadership before building out an in-house group.

Pharmaceutical companies

R&D groups looking for an outside perspective on a stalled series, a new modality, or a portfolio decision.

Investors and venture firms

Funds that need rigorous, independent scientific assessment of assets and companies before they commit.

Academic spin-outs

Researchers translating a discovery into a drug program with a credible path to the clinic.

How an engagement works

Every program is different, but our work follows a clear path so you always know where things stand.

  1. Understand

    We review your data, goals, and constraints in a confidential introductory conversation.

  2. Assess

    We identify the key scientific risks and opportunities in your program or asset.

  3. Recommend

    You receive a clear plan with prioritized actions, decision points, and resourcing options.

  4. Deliver

    We stay alongside your team through execution, from design cycles to board presentations.

About Aalo Bio

In Bengali and Hindi, aalo means light. That is the work we do: bringing clarity to complex scientific problems so our clients can make better decisions, faster.

Aalo Bio was founded by a group of scientists with experience across academia, biotech, and pharma, spanning multiple therapeutic areas and modalities. We combine bench-level understanding of drug discovery and medicinal chemistry with the strategic perspective needed to build programs that reach patients.

The best drug programs are built on clear thinking long before they are built on compounds.

Debatosh Majumdar, PhD

Principal Consultant

Debatosh is an organic and medicinal chemist with more than two decades of research experience, including over ten years in biotech and pharma drug discovery. He has guided programs from hit identification through lead optimization to preclinical candidate nomination, with oncology, fibrosis, CNS, and infectious disease programs advanced into IND-enabling in vivo studies.

He is known for working closely with biology, DMPK, computational chemistry, and CRO partners, mentoring scientists, and explaining complex data clearly to project teams and senior leadership.

Therapeutic areas

  • Oncology
  • Infectious disease
  • CNS and neuroscience
  • Fibrosis and inflammation

Modalities

  • Small molecules
  • Oligonucleotides and siRNA
  • Peptides, peptidomimetics, and carbohydrates
  • Bioconjugates, proteins, and antibodies

Start a conversation

Tell us a little about your program or question. We respond within two business days, and all initial discussions are confidential.

Email us directly at
info@AaloBio.com

Sending opens your email app with your message ready to go.